methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Base Information

Chemical Name:methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate
CAS No.:173987-69-4
Molecular Formula:C₄₂H₅₀F₃NO₁₄
Molecular Weight:849.853
Hs Code.:

methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Synonyms:methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Suppliers and Price of methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

There total 11 articles about methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 173987-68-3
methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-3-deoxy-7,8-O-isopropylidene-5-O-(3,4,6-tri-O-acetyl-2-O-benzyl-α-D-glucopyranosyl)-α-D-manno-oct-2-ulopyranosid>onate

: 173987-69-4
methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Guidance literature:: With methanol; sodium methylate; for 7h; Ambient temperature;
DOI:10.1016/0008-6215(95)00269-3

Reference yield:

: 85382-90-7
methyl-4,5,7,8-tetra-O-acetyl-2,6-anhydro-2,3-dideoxy-D-manno-oct-2-enosonat

: 173987-69-4
methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) silver trifluoromethanesulfonate, Me₃Si triflate / 1.) CH₂Cl₂, 0 deg C, 30 min, 2.) CH₂Cl₂, 2 h

2: triphenyltin hydride, azobisisobutyronitrile / toluene / 0.5 h / Heating

3: NaOMe, MeOH / 2 h / Ambient temperature

4: p-toluenesulfonic acid / dimethylformamide / 20 h

5: 1.) dibutyltin oxide, 2.) tetrabutylammonium iodide, 3.) NaOMe, MeOH

6: 84 percent / dimethyl(methylthio)sulfonium trifluoromethanesulfonate, 4 Angstroem molecular sieves / CH₂Cl₂ / 18 h / 0 - 20 °C

7: 83 percent / NaOMe, MeOH / 7 h / Ambient temperature

With methanol; 2,2'-azobis(isobutyronitrile); trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; triphenylstannane; sodium methylate; silver trifluoromethanesulfonate; tetra-(n-butyl)ammonium iodide; di(n-butyl)tin oxide; toluene-4-sulfonic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1016/0008-6215(95)00269-3

Reference yield:

: 173987-57-0
ethyl 2-O-benzyl-1-thio-β-D-glucopyranoside

: 173987-69-4
methyl <2-(4-trifluoroacetamidophenyl)ethyl 4-O-benzyl-5-O-(2-O-benzyl-α-D-glucopyranosyl)-3-deoxy-7,8-O-isopropylidene-α-D-manno-oct-2-ulopyranosid>onate

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / pyridine / 2 h / Ambient temperature

2: 84 percent / dimethyl(methylthio)sulfonium trifluoromethanesulfonate, 4 Angstroem molecular sieves / CH₂Cl₂ / 18 h / 0 - 20 °C

3: 83 percent / NaOMe, MeOH / 7 h / Ambient temperature

With pyridine; methanol; 4 A molecular sieve; sodium methylate; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In dichloromethane;
DOI:10.1016/0008-6215(95)00269-3