Magnesium orotate

Base Information

• Chemical Name: Magnesium orotate
• CAS No.: 34717-03-8
• Deprecated CAS: 11097-30-6,27067-77-2
• Molecular Formula: C10H6MgN4O8
• Molecular Weight: 334.48
• European Community (EC) Number: 252-167-6
• UNII: GI96W46M5A
• DSSTox Substance ID: DTXSID20905129
• Wikipedia: Magnesium_orotate
• Wikidata: Q9053193
• NCI Thesaurus Code: C87337
• ChEMBL ID: CHEMBL3707282
• Mol file: 34717-03-8.mol

Synonyms:magnesium orotate

Chemical Property of Magnesium orotate

Chemical Property:

• Appearance/Colour: A white to almost white crystalline powder.
• PSA: 184.04000
• LogP: -2.63140
• Storage Temp.: -20°C
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 0
• Exact Mass: 334.0036049
• Heavy Atom Count: 23
• Complexity: 262

Purity/Quality:

99% ^*data from raw suppliers

Tubulin, beta 3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(NC(=O)NC1=O)C(=O)[O-].C1=C(NC(=O)NC1=O)C(=O)[O-].[Mg+2]
• Recent EU Clinical Trials: MACH 2 - Magnesium orotate in severe congestive heart failure - Part 2
• Description: Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers. Experiments investigating the potential cardioprotective actions of orotic acid in pathological heart conditions are still ongoing.
• Uses: magnesium orotate is used as an adjuvant treatment in congestive heart failure, hyperten-sion, post-operative cardiac status or in type 2 diabetes.Magnesium orotate combines in itself the cardio protective properties of magnesium and orotic acid and leads to the optimisation of the magnesium effect by reducing cellular magnesium loss.At the same time, animal studies have indicated a protective effect of magnesium orotate with respect to atherosclerotic vascular changes. The efficacy of the combination was superior to the effect of the individual components of magnesium and orotic acid.