2-amino-4-bromo-6-deuteronitrobenzene

Base Information

• Chemical Name: 2-amino-4-bromo-6-deuteronitrobenzene
• CAS No.: 353491-34-6
• Molecular Formula: C₆H₅BrN₂O₂
• Molecular Weight: 218.014
• Mol file: 353491-34-6.mol

Synonyms:2-amino-4-bromo-6-deuteronitrobenzene

Chemical Property of 2-amino-4-bromo-6-deuteronitrobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-4-bromo-6-deuteronitrobenzene

There total 3 articles about 2-amino-4-bromo-6-deuteronitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-bromo-6-deuterio-2-fluoronitrobenzene (251372-06-2) → 2-amino-4-bromo-6-deuteronitrobenzene (353491-34-6)

Guidance literature:

With ammonia; at -35 - 0 ℃;

DOI:10.1016/S0040-4020(01)00398-2

Reference yield:

4-bromo-2-fluoroaniline (367-24-8) → 2-amino-4-bromo-6-deuteronitrobenzene (353491-34-6)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂; D₂O / Heating

2: 52 percent / Oxone; NaHCO₃ / H₂O; acetone

3: 97 percent / liq. NH₃ / -35 - 0 °C

With Oxone; thionyl chloride; ammonia; water-d2; sodium hydrogencarbonate; In water; acetone;

DOI:10.1016/S0040-4020(01)00398-2

Reference yield:

C6H4(2)HBrFN → 2-amino-4-bromo-6-deuteronitrobenzene (353491-34-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / Oxone; NaHCO₃ / H₂O; acetone

2: 97 percent / liq. NH₃ / -35 - 0 °C

With Oxone; ammonia; sodium hydrogencarbonate; In water; acetone;

DOI:10.1016/S0040-4020(01)00398-2

upstream raw materials:

4-bromo-6-deuterio-2-fluoronitrobenzene

4-bromo-2-fluoroaniline

Downstream raw materials:

4-bromo-2-deuterionitrobenzene

Refernces