1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine

Base Information

Chemical Name:1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine
CAS No.:83409-03-4
Molecular Formula:C₂₈H₃₅N₃O₅
Molecular Weight:493.603
Hs Code.:
DSSTox Substance ID:DTXSID501003406

Synonyms:BRN 4613534;1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine;Piperidine, 1-(4-methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)-;DTXSID501003406;LS-115727;3-[4-Methyl-1-oxo-1-(piperidin-1-yl)pentan-2-yl]-2-(3,4,5-trimethoxyphenyl)quinazolin-4(3H)-one

Suppliers and Price of 1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-METHYL-2-(4-OXO-2-(3,4,5-TRIMETHOXYPHENYL)-3(4H)-QUINAZOLINYL)PEN TYL)PIPERIDINE 95.00%
5MG
$ 504.49

Total 0 raw suppliers

Chemical Property of 1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine

Chemical Property:

Vapor Pressure:4.18E-17mmHg at 25°C
Boiling Point:656.4°C at 760 mmHg
Flash Point:350.8°C
PSA：65.82000
Density:1.21g/cm³
LogP:5.10030
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:493.25767123
Heavy Atom Count:36
Complexity:782

Purity/Quality:: 1-(4-METHYL-2-(4-OXO-2-(3,4,5-TRIMETHOXYPHENYL)-3(4H)-QUINAZOLINYL)PEN TYL)PIPERIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)N1CCCCC1)N2C(=NC3=CC=CC=C3C2=O)C4=CC(=C(C(=C4)OC)OC)OC

Technology Process of 1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine

There total 5 articles about 1-(4-Methyl-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)pentyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 110-89-4
piperidine

: 83409-28-3
4-Methyl-2-[4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-pentanoyl chloride

: 83409-03-4
3-[3-Methyl-1-(piperidine-1-carbonyl)-butyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: In benzene; for 2h; Heating;

Reference yield:

: 40728-74-3
2-(3,4,5-trimethoxyphenyl)-4-H-benzo[d][1,3]oxazin-4-one

: 83409-03-4
3-[3-Methyl-1-(piperidine-1-carbonyl)-butyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent / pyridine; H₂O / 10 h / Heating

2: SOCl₂ / benzene / 6 h / Heating

3: 70 percent / benzene / 2 h / Heating

With thionyl chloride; In pyridine; water; benzene;

Reference yield:

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 83409-03-4
3-[3-Methyl-1-(piperidine-1-carbonyl)-butyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 72 percent / pyridine; H₂O / 10 h / Heating

3: SOCl₂ / benzene / 6 h / Heating

4: 70 percent / benzene / 2 h / Heating

With pyridine; thionyl chloride; In pyridine; water; benzene;