C₃₃H₂₉FN₄O₇

Base Information

• Chemical Name: C₃₃H₂₉FN₄O₇
• CAS No.: 1403851-15-9
• Molecular Formula: C₃₃H₂₉FN₄O₇
• Molecular Weight: 612.614
• Mol file: 1403851-15-9.mol

Synonyms:C₃₃H₂₉FN₄O₇

Chemical Property of C₃₃H₂₉FN₄O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₂₉FN₄O₇

There total 5 articles about C₃₃H₂₉FN₄O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C34H31FN4O7 (1403851-14-8) → C33H29FN4O7 (1403851-15-9)

Guidance literature:

C₃₄H₃₁FN₄O₇; With water; lithium hydroxide; In methanol; at 20 ℃; for 18h; Cooling with ice;

With hydrogenchloride; In methanol; water; at 10 ℃;

Reference yield:

DL-5-fluorotryptophan (154-08-5,343-91-9,97749-24-1) → C33H29FN4O7 (1403851-15-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: chloro-trimethyl-silane / 20 h / 0 - 20 °C

2.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C

3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 1 h / 85 °C

4.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h

5.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C

6.1: potassium carbonate; N,N,N,N-tetraethylammonium tetrafluoroborate / N,N-dimethyl-formamide; water / 72 h / Electrochemical reaction

7.1: water; lithium hydroxide / methanol / 18 h / 20 °C / Cooling with ice

7.2: 10 °C

With chloro-trimethyl-silane; water; hydrogen; N,N,N,N-tetraethylammonium tetrafluoroborate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

Reference yield:

5-fluoro-DL-tryptophan methyl ester hydrochloride → C33H29FN4O7 (1403851-15-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C

2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 1 h / 85 °C

3.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h

4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C

5.1: potassium carbonate; N,N,N,N-tetraethylammonium tetrafluoroborate / N,N-dimethyl-formamide; water / 72 h / Electrochemical reaction

6.1: water; lithium hydroxide / methanol / 18 h / 20 °C / Cooling with ice

6.2: 10 °C

With water; hydrogen; N,N,N,N-tetraethylammonium tetrafluoroborate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

upstream raw materials:

DL-5-fluorotryptophan

C₂₅H₂₈FN₃O₅

C₂₅H₂₄FN₃O₅

C₃₄H₃₁FN₄O₇

Refernces