Technology Process of C18H21N3O2
There total 2 articles about C18H21N3O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: piperidine / dichloromethane / 0.17 h / 20 °C
1.2: 0.17 h / 20 °C
2.1: sodium tetrahydroborate / isopropyl alcohol; water / 1 h / 60 °C
2.2: 48 h / 20 - 80 °C
With
piperidine; sodium tetrahydroborate;
In
dichloromethane; water; isopropyl alcohol;
1.1: Knoevenagel Condensation;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trichlorophosphate / pyridine / 24 h / 0 - 20 °C / Inert atmosphere
2.1: piperidine / dichloromethane / 0.17 h / 20 °C
2.2: 0.17 h / 20 °C
3.1: sodium tetrahydroborate / isopropyl alcohol; water / 1 h / 60 °C
3.2: 48 h / 20 - 80 °C
With
piperidine; sodium tetrahydroborate; trichlorophosphate;
In
pyridine; dichloromethane; water; isopropyl alcohol;
1.1: Vilsmeier Formylation / 2.1: Knoevenagel Condensation;
- Guidance literature:
-
With
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 48h;
Inert atmosphere;