benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

Base Information

Chemical Name:benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate
CAS No.:83089-96-7
Molecular Formula:C₃₀H₃₈N₂O₆
Molecular Weight:522.642
Hs Code.:

Synonyms:benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

Suppliers and Price of benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

There total 2 articles about benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 51089-83-9
benzyl 4-ethyl-3-methyl-1H-pyrrole-2-carboxylate

: 30089-44-2
tert-butyl 5-acetoxymethyl-4-(2-methoxycarbonylethyl)-3-methyl-pyrrole-2-carboxylate

: 83089-96-7
benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

Guidance literature:: With sodium acetate; In acetic acid; for 0.666667h; Heating;

Reference yield:

: 83089-91-2
benzyl 3-ethyl-2-iodo-4-methylpyrrole-5-carboxylate

: 83089-96-7
benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, sodium acetate / Adams platinum oxide catalyst / methanol / 3 h / Ambient temperature

2: 71 percent / sodium acetate / acetic acid / 0.67 h / Heating

With hydrogen; sodium acetate; platinum(IV) oxide; In methanol; acetic acid;

Reference yield:

: 83089-96-7
benzyl 5'-t-butoxycarbonyl-3-ethyl-3'-(2-methoxycarbonylethyl)-4,4'-dimethyldipyrrylmethane-5-carboxylate

: 3-((5Z,10Z,14Z,19Z)-8-Butyl-18-ethyl-3,7,12,13,17-pentamethyl-5-phenyl-porphyrin-2-yl)-propionic acid

Guidance literature:: Multi-step reaction with 5 steps

1: H₂; Et₃N / Pd-C / tetrahydrofuran / 25 °C

2: pTsOH / CH₂Cl₂ / 25 °C

3: K₂CO₃; POCl₃ / CH₂Cl₂ / 0 - 25 °C

4: 100 percent / LiOH; H₂O / tetrahydrofuran / 18 h / 25 °C

With lithium hydroxide; water; hydrogen; potassium carbonate; toluene-4-sulfonic acid; triethylamine; trichlorophosphate; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; 1: Hydrogenolysis / 2: Decarboxylation / 3: Vilsmeier formylation / 4: Hydrolysis;
DOI:10.1016/S0040-4039(00)01269-7