C₆₅H₁₀₅NO₁₆Si

Base Information

• Chemical Name: C₆₅H₁₀₅NO₁₆Si
• CAS No.: 1246021-94-2
• Molecular Formula: C₆₅H₁₀₅NO₁₆Si
• Molecular Weight: 1184.63
• Mol file: 1246021-94-2.mol

Synonyms:C₆₅H₁₀₅NO₁₆Si

Chemical Property of C₆₅H₁₀₅NO₁₆Si

Chemical Property:

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Technology Process of C₆₅H₁₀₅NO₁₆Si

There total 1 articles about C₆₅H₁₀₅NO₁₆Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

31-(triethylsilylether)rapamycin (179076-04-1) + 2,2,5-trimethyl-1,3-dioxane-5-carboxylic anhydride (408322-03-2) → C65H105NO16Si (1246021-94-2)

Guidance literature:

With dmap; In dichloromethane; at 20 ℃; Inert atmosphere;

Reference yield: 77.1%

C65H105NO16Si (1246021-94-2) → temsirolimus (162635-04-3,343261-52-9)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; water; at 0 - 5 ℃; for 50.5h;

upstream raw materials:

31-(triethylsilylether)rapamycin

2,2,5-trimethyl-1,3-dioxane-5-carboxylic anhydride

Downstream raw materials:

temsirolimus

Refernces