Technology Process of 3,3'-(1,22-Docosandiyl)bis(4,5-dimethoxybenzolnonanol)
There total 11 articles about 3,3'-(1,22-Docosandiyl)bis(4,5-dimethoxybenzolnonanol) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 54 percent / Na / methanol / 8 h / 20 - 30 °C / electrolysis
2: 91.5 percent / dimethylformamide / 24 h / Heating
3: 15percent n-BuLi / diethyl ether; tetrahydrofuran; hexane / 0.5 h / 0 °C
4: tetrahydrofuran / 2 h / Ambient temperature
5: 90 percent / 20percent diisobutylaluminium hydride / benzene; toluene / 14 h / Ambient temperature
6: 1.) 15percent n-BuLi / 1.) THF, hexane, 30 min, 0 deg C, 2.) THF, hexane, 2 h, r.t.
7: 1.) H2, 2.) 2 N H2SO4 / 10percent Pd/C / 1.) THF, 12 h, 2.) ethanol, 8 h, reflux
With
n-butyllithium; sulfuric acid; hydrogen; sodium; diisobutylaluminium hydride;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; hexane; N,N-dimethyl-formamide; toluene; benzene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 91.5 percent / dimethylformamide / 24 h / Heating
2: 15percent n-BuLi / diethyl ether; tetrahydrofuran; hexane / 0.5 h / 0 °C
3: tetrahydrofuran / 2 h / Ambient temperature
4: 90 percent / 20percent diisobutylaluminium hydride / benzene; toluene / 14 h / Ambient temperature
5: 1.) 15percent n-BuLi / 1.) THF, hexane, 30 min, 0 deg C, 2.) THF, hexane, 2 h, r.t.
6: 1.) H2, 2.) 2 N H2SO4 / 10percent Pd/C / 1.) THF, 12 h, 2.) ethanol, 8 h, reflux
With
n-butyllithium; sulfuric acid; hydrogen; diisobutylaluminium hydride;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; hexane; N,N-dimethyl-formamide; toluene; benzene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2.) 10percent FeCl3, HCl / 1.) DMF, 150 deg C, 14 h, 2.) DMF
2: tetrahydrofuran / 2 h / Ambient temperature
3: 90 percent / 20percent diisobutylaluminium hydride / benzene; toluene / 14 h / Ambient temperature
4: 1.) 15percent n-BuLi / 1.) THF, hexane, 30 min, 0 deg C, 2.) THF, hexane, 2 h, r.t.
5: 1.) H2, 2.) 2 N H2SO4 / 10percent Pd/C / 1.) THF, 12 h, 2.) ethanol, 8 h, reflux
With
hydrogenchloride; n-butyllithium; sulfuric acid; hydrogen; iron(III) chloride; diisobutylaluminium hydride;
palladium on activated charcoal;
In
tetrahydrofuran; toluene; benzene;