Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate

Base Information

Chemical Name:Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate
CAS No.:72758-46-4
Molecular Formula:C₁₃H₁₈N₆O₅
Molecular Weight:338.323
Hs Code.:
DSSTox Substance ID:DTXSID10223066
Wikidata:Q76155391

Synonyms:Adenosine-5'-(N-propoxy)carboxamide hemihydrate;Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate;1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-propoxyribofuranuronamide hemihydrate;72758-46-4;DTXSID10223066;C13H18N6O5.1/2H2O;LS-143780;C13-H18-N6-O5.1/2H2-O

Suppliers and Price of Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate

Chemical Property:

Density:1.81g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:5
Exact Mass:338.13386770
Heavy Atom Count:24
Complexity:457

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCONC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
Isomeric SMILES:CCCONC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O

Technology Process of Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate

There total 2 articles about Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-propoxy-, hemihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid propoxy-amide

: 72758-46-4
(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid propoxy-amide

Guidance literature:: With formic acid; at 70 ℃; for 1h;
DOI:10.1021/jm00177a021

Reference yield:

: 39491-49-1
2',3'-O-isopropylideneadenosine-5'-carbonyl chloride

: 72758-46-4
(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid propoxy-amide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CHCl₃ / 15 h / Ambient temperature

2: 50percent aq. HCOOH / 1 h / 70 °C

With formic acid; triethylamine; In chloroform;
DOI:10.1021/jm00177a021