1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Base Information

Chemical Name:1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
CAS No.:98534-86-2
Molecular Formula:C₁₀H₆F₃N₃O₂
Molecular Weight:257.172
Hs Code.:
European Community (EC) Number:820-620-2
ChEMBL ID:CHEMBL5174352
DSSTox Substance ID:DTXSID201166801

Synonyms:98534-86-2;1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid;CHEMBL5174352;1-pyridin-2-yl-5-(trifluoromethyl)pyrazole-4-carboxylic acid;1-pyridin-2-yl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid;SCHEMBL1335647;DTXSID201166801;1-(2-Pyridinyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid;BDBM50601789;AKOS000145116;MCULE-3571691672;DB-323029;EN300-36069;G54205;Z241107286;1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid;1-(pyridin-2-yl)-5-(trifluoromethyl)pyrazole-4-carboxylic acid;1H-Pyrazole-4-carboxylic acid, 1-(2-pyridinyl)-5-(trifluoromethyl)-

Suppliers and Price of 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
1-(Pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
500mg
$ 532.00

AK Scientific
1-(Pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
100mg
$ 262.00

Total 5 raw suppliers

Chemical Property of 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:257.04121093
Heavy Atom Count:18
Complexity:324

Purity/Quality:

98% ^*data from raw suppliers

1-(Pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)N2C(=C(C=N2)C(=O)O)C(F)(F)F

Technology Process of 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

There total 1 articles about 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1236148-82-5
ethyl 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate

: 98534-86-2
1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: ethyl 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate; With ethanol; sodium hydroxide; at 20 ℃; for 1h;

With hydrogenchloride; In water;

Reference yield:

: N'-hydroxy-4-(hydroxymethyl)benzimidamide

: 98534-86-2
1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

: 1236148-83-6
(4-(5-(1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)phenyl)methanol

Guidance literature:: 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.666667h;

N'-hydroxy-4-(hydroxymethyl)benzimidamide; In N,N-dimethyl-formamide; at 20 ℃; for 7h;

Reference yield:

: 1236148-81-4,852691-00-0
(Z)-4-(1,3-dioxolan-2-yl)-N'-hydroxybenzimidamide

: 98534-86-2
1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

: 1236148-85-8
3-(4-(1,3-dioxolan-2-yl)phenyl)-5-(1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazole

Guidance literature:: 1-(pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

(Z)-4-(1,3-dioxolan-2-yl)-N'-hydroxybenzimidamide; In N,N-dimethyl-formamide; at 140 ℃; for 4h;