(Z)-4-Amino-alpha-phenylcinnamic acid

Base Information

Chemical Name:(Z)-4-Amino-alpha-phenylcinnamic acid
CAS No.:52873-64-0
Molecular Formula:C₁₅H₁₃NO₂
Molecular Weight:239.274
Hs Code.:
DSSTox Substance ID:DTXSID401205483
Nikkaji Number:J1.421.513A

Synonyms:52873-64-0;(2{Z})-3-(4-aminophenyl)-2-phenylacrylic acid;DTXSID401205483;AKOS003268344;(Z)-4-Amino-alpha-phenylcinnamic acid;Benzeneacetic acid, .alpha.-[(4-aminophenyl)methylidene]-;Benzeneacetic acid, alpha-[(4-aminophenyl)methylene]-, (Z)-

Suppliers and Price of (Z)-4-Amino-alpha-phenylcinnamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-4-Amino-alpha-phenylcinnamic acid

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:239.094628657
Heavy Atom Count:18
Complexity:311

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=CC2=CC=C(C=C2)N)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)/C(=C/C2=CC=C(C=C2)N)/C(=O)O

Technology Process of (Z)-4-Amino-alpha-phenylcinnamic acid

There total 5 articles about (Z)-4-Amino-alpha-phenylcinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 52873-64-0
(2Z)-3-(4-aminophenyl)-2-phenylprop-2-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride; triethylamine / 95 - 100 °C

2: sodium hydrogen sulfide / methanol / 95 - 100 °C

With sodium hydrogen sulfide; acetic anhydride; triethylamine; In methanol; 1: |Perkin Carboxylic Acid Synthesis;
DOI:10.1016/j.bioorg.2018.11.026

Reference yield:

: 103-82-2
phenylacetic acid

: 52873-64-0
(2Z)-3-(4-aminophenyl)-2-phenylprop-2-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride; triethylamine / 95 - 100 °C

2: sodium hydrogen sulfide / methanol / 95 - 100 °C

With sodium hydrogen sulfide; acetic anhydride; triethylamine; In methanol; 1: |Perkin Carboxylic Acid Synthesis;
DOI:10.1016/j.bioorg.2018.11.026

Reference yield:

: 19319-30-3
(E)-2-phenyl-3-(4-nitrophenyl)propenoic acid

: 52873-64-0
(2Z)-3-(4-aminophenyl)-2-phenylprop-2-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: FeSO₄; aqueous NH₃

2: Irradiation_.Einwirkung von UV-Licht

With ammonium hydroxide; iron(II) sulfate;
DOI:10.1039/jr9550003445