3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone

Base Information

• Chemical Name: 3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone
• CAS No.: 1266580-25-9
• Molecular Formula: C₁₆H₂₅N₃OS
• Molecular Weight: 307.46
• Mol file: 1266580-25-9.mol

Synonyms:3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone

Chemical Property of 3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone

There total 1 articles about 3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.5%

3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) + thiosemicarbazide (79-19-6) → 3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone (1266580-25-9)

Guidance literature:

With trifluoroacetic acid; In ethanol; for 2h; Reflux;

DOI:10.1134/S1070363216030166

Reference yield: 88.0%

[Cu2(OAc)4(H2O)2] (879089-16-4,155065-88-6) + 3,5-di-tert-butyl-2-hydroxybenzaldehyde thiosemicarbazone (1266580-25-9) → H2NC(S)NHNCHC6H2(O)(C(CH3)3)2(1-)*Cu(1+)=Cu(H2NC(S)NHNCHC6H2(O)(C(CH3)3)2)

Guidance literature:

In methanol; ethanol; Cu acetate in MeOH added dropwise to hot soln. of thiosemicarbazone in EtOH (75°C), reflux for 2.5 h; recrystn. (refluxing EtOH), suspended in cold EtOH, centrifugation, suspended in Et2O, centrifugation, dried (vac.); elem. anal.;

DOI:10.1016/j.jorganchem.2012.03.018

upstream raw materials:

3,5-di-tert-butyl-2-hydroxybenzaldehyde

thiosemicarbazide