ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate

Base Information

• Chemical Name: ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate
• CAS No.: 135969-88-9
• Molecular Formula: C₃₅H₃₁NO₄
• Molecular Weight: 529.635
• Mol file: 135969-88-9.mol

Synonyms:ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate

Chemical Property of ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate

Chemical Property:

Purity/Quality:

ETHYL 3-BENZOYL-1-CYANO-4-HYDROXY-2,4,6-TRIPHENYLCYCLOHEXANECARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate

There total 6 articles about ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

benzalacetophenone (94-41-7) + ethyl 2-cyanoacetate (105-56-6) → ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate (135969-88-9)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In water; at 80 ℃; for 0.5h;

DOI:10.3184/174751911X12977065405044

Reference yield: 85.0%

benzalacetophenone (94-41-7) + ethyl 2-cyanoacetate (105-56-6) → 2-benzoyl-4-carboethoxy-4-cyano-1,3,5-triphenylcyclohexanol (81280-90-2,135969-88-9)

Guidance literature:

With sodium ethanolate; In ethanol; Ambient temperature;

DOI:10.1016/S0040-4020(01)89531-4

Reference yield: 84.0%

3-benzoyl-1-cyano-1-ethoxycarbonyl-2-phenylpropane (109694-24-8) → ethyl 3-benzoyl-1-cyano-4-hydroxy-2,4,6-triphenylcyclohexanecarboxylate (135969-88-9)

Guidance literature:

With sodium ethanolate; In ethanol; Heating;

upstream raw materials:

benzalacetophenone

ethyl 2-cyanoacetate

3-benzoyl-1-cyano-1-ethoxycarbonyl-2-phenylpropane

1,3-diphenyl-propen-3-one

Downstream raw materials:

5-Benzoyl-1-cyano-2,4,6-triphenyl-cyclohex-3-enecarboxylic acid ethyl ester

ethyl 2-cyanoacetate

1,3-diphenyl-propen-3-one