(1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester

Base Information

• Chemical Name: (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester
• CAS No.: 75201-83-1
• Molecular Formula: C₁₇H₁₄N₂O₃
• Molecular Weight: 294.31
• Mol file: 75201-83-1.mol

Synonyms:(1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester

Chemical Property of (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester

There total 3 articles about (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-aminoisoquinolin-1(2H)-one (93117-08-9) + benzyl chloroformate (501-53-1,94274-21-2) → (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester (75201-83-1)

Guidance literature:

With pyridine; In acetone; at 20 ℃;

DOI:10.1021/jm050896o

Reference yield:

(2-Oxy-isoquinolin-5-yl)-carbamic acid benzyl ester (75201-77-3) → (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester (75201-83-1)

Guidance literature:

In methanol; Yield given; Irradiation;

DOI:10.1246/cl.1980.547

Reference yield:

(2-Oxy-isoquinolin-5-yl)-carbamic acid benzyl ester (75201-77-3) → (1-Oxo-1,2-dihydro-isoquinolin-5-yl)-carbamic acid benzyl ester (75201-83-1) + (5-Oxa-7-aza-benzocyclohepten-1-yl)-carbamic acid benzyl ester

Guidance literature:

In acetone; Irradiation;

DOI:10.1246/cl.1980.547

upstream raw materials:

(2-Oxy-isoquinolin-5-yl)-carbamic acid benzyl ester

5-aminoisoquinolin-1(2H)-one

benzyl chloroformate