(3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

Base Information

Chemical Name:(3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline
CAS No.:260996-16-5
Molecular Formula:C₂₅H₃₅NO₂
Molecular Weight:381.558
Hs Code.:

Synonyms:(3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

Suppliers and Price of (3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

Chemical Property:

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Technology Process of (3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

There total 3 articles about (3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-24-1
trimethylaluminum

: 260995-95-7
C₂₄H₃₁NO₂

: 260996-16-5
(3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

: (1R,2S,5R)-5-Methyl-2-[1-methyl-1-((1R,2R,5R,6R,7S)-2-methyl-6-phenyl-10-oxa-3-aza-tricyclo[5.2.1.0^1,5]dec-8-en-3-yl)-ethyl]-cyclohexanol

Guidance literature:: In toluene; at 20 ℃;
DOI:10.1021/jo991544q

Reference yield:

: 98-01-1
furfural

: 260996-16-5
(3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / Heating

2: 50 percent / toluene / 300 h / Heating

3: toluene / 20 °C

In toluene; 1: Cycloaddition / 2: Cyclization / 3: Ring cleavage;
DOI:10.1021/jo991544q

Reference yield:

: 260995-89-9
N-cinnamyl-2α-(2-furyl)-4,4,7α-trimethyl-trans-octahydro-1,3-benzoxazine

: 260996-16-5
(3S,3aR,6S,7S,7aR)-N-(8-mentholyl)-3a,6-epoxy-3-methyl-7-phenyl-3a,6,7,7a-tetrahydroisoindoline

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / toluene / 300 h / Heating

2: toluene / 20 °C

In toluene; 1: Cyclization / 2: Ring cleavage;
DOI:10.1021/jo991544q