Technology Process of C24H27N5O2
There total 5 articles about C24H27N5O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutylammomium bromide; potassium hydroxide;
In
tetrahydrofuran; water;
at 50 ℃;
for 48h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogen / methanol; tetrahydrofuran / 1.5 h / 20 °C / 2250.23 Torr
2: caesium carbonate; XPhos; tris-(dibenzylideneacetone)dipalladium(0) / 18 h / 100 °C / Inert atmosphere
3: potassium hydroxide; tetrabutylammomium bromide / water; tetrahydrofuran / 48 h / 50 °C
With
tris-(dibenzylideneacetone)dipalladium(0); tetrabutylammomium bromide; hydrogen; caesium carbonate; potassium hydroxide; XPhos;
In
tetrahydrofuran; methanol; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: caesium carbonate; XPhos; tris-(dibenzylideneacetone)dipalladium(0) / 18 h / 100 °C / Inert atmosphere
2: potassium hydroxide; tetrabutylammomium bromide / water; tetrahydrofuran / 48 h / 50 °C
With
tris-(dibenzylideneacetone)dipalladium(0); tetrabutylammomium bromide; caesium carbonate; potassium hydroxide; XPhos;
In
tetrahydrofuran; water;