N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

Base Information

Chemical Name:N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide
CAS No.:1187843-18-0
Molecular Formula:C₃₀H₃₆N₂O₆
Molecular Weight:520.626
Hs Code.:

Synonyms:N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

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Technology Process of N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

There total 1 articles about N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 4593-90-2,772-17-8
3-phenylbutyric acid

: 76646-41-8
4-methoxy-3-(methoxymethyl)benzaldehyde

: 588708-17-2
1-(isocyanomethyl)-2,4-dimethoxybenzene

: 1187843-18-0
N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

Guidance literature:: With ammonia; In 2,2,2-trifluoroethanol; water; at 20 ℃;
DOI:10.1021/jo9014529

Reference yield:

: 1187843-18-0
N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

: 1187843-22-6
N-(2,4-dimethoxybenzyl)-4-(4-methoxy-3-(methoxymethyl)phenyl)-2-(2-phenylpropyl)thiazol-5-amine

Guidance literature:: With Lawessons reagent; In toluene; for 1h; Inert atmosphere; Reflux;
DOI:10.1021/jo9014529

Reference yield:

: 1187843-18-0
N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide

: 407-25-0
trifluoroacetic anhydride

: 1187843-29-3
2,2,2-trifluoro-N-(4-(4-methoxy-3-(methoxymethyl)phenyl)-2-(2-phenylpropyl)oxazol-5-yl)acetamide

Guidance literature:: N-(2-(2,4-dimethoxybenzylamino)-1-(4-methoxy-3-(methoxymethyl)phenyl)-2-oxoethyl)-3-phenylbutanamide; With trifluoroacetic acid; In dichloromethane; for 0.333333h;

trifluoroacetic anhydride; In dichloromethane; for 0.666667h;
DOI:10.1021/jo9014529