(E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate

Base Information

• Chemical Name: (E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate
• CAS No.: 1356915-83-7
• Molecular Formula: C₂₄H₃₀N₂O₆S
• Molecular Weight: 474.578
• Mol file: 1356915-83-7.mol

Synonyms:(E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate

Chemical Property of (E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate

There total 1 articles about (E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

methyl N-(2,2-diphenylpent-4-enyl)sulfamoylcarbamate (958264-12-5) + tert-Butyl acrylate (1663-39-4,25232-27-3) → (E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate (1356915-83-7)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; In dichloromethane; at 40 ℃; for 3h; Inert atmosphere;

DOI:10.1021/jo202507d

Reference yield: 76.0%

(E)-tert-butyl 6-((N-(methoxycarbonyl)sulfamoyl)amino)-5,5-diphenylhex-2-enoate (1356915-83-7) → syn-3-tert-butyl 2-methyl 5,5-diphenyltetrahydropyrrolo[1,2-b][1,2,5]-thiadiazole-2,3(3H)-dicarboxylate 1,1-dioxide + anti-3-tert-butyl 2-methyl 5,5-diphenyltetrahydropyrrolo[1,2-b][1,2,5]-thiadiazole-2,3(3H)-dicarboxylate 1,1-dioxide

Guidance literature:

With palladium diacetate; caesium carbonate; copper(ll) bromide; In N,N-dimethyl-formamide; at 40 ℃; for 12h; optical yield given as %de; diastereoselective reaction;

DOI:10.1021/jo202507d

upstream raw materials:

methyl N-(2,2-diphenylpent-4-enyl)sulfamoylcarbamate

tert-Butyl acrylate