((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane

Base Information

• Chemical Name: ((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane
• CAS No.: 1187531-62-9
• Molecular Formula: C₁₉H₃₀O₂Si
• Molecular Weight: 318.531
• Mol file: 1187531-62-9.mol

Synonyms:((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane

Chemical Property of ((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane

There total 1 articles about ((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(E)-6-(benzyloxy)hex-4-en-3-one (1187531-64-1) + triethylsilyl trifluoromethyl sulfonate (79271-56-0) → ((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane (1187531-62-9)

Guidance literature:

With triethylamine; In diethyl ether; at -78 - 0 ℃; Inert atmosphere;

DOI:10.1021/ol901691d

Reference yield: 52.0%

((2Z,4E)-6-(benzyloxy)hexa-2,4-dien-3-yloxy)triethylsilane (1187531-62-9) + 3-(tert-butyldimethylsilanyloxy)propionaldehyde (89922-82-7) → ((2S,3R,6S)-6-(benzyloxymethyl)-2-(2-(tert-butyldimethylsilyloxy)ethyl)-3-methyl-3,6-dihydro-2H-pyran-4-yloxy)triethylsilane (1187531-65-2)

Guidance literature:

With (1R,2S) Jacobsen's chromium catalyst; for 168h; optical yield given as %ee; diastereoselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1021/ol901691d

upstream raw materials:

(E)-6-(benzyloxy)hex-4-en-3-one

triethylsilyl trifluoromethyl sulfonate

Downstream raw materials:

((2S,3R,6S)-6-(benzyloxymethyl)-2-(2-(tert-butyldimethylsilyloxy)ethyl)-3-methyl-3,6-dihydro-2H-pyran-4-yloxy)triethylsilane