α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester

Base Information

• Chemical Name: α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester
• CAS No.: 89908-40-7
• Molecular Formula: C₂₂H₂₄O₃
• Molecular Weight: 336.431
• Mol file: 89908-40-7.mol

Synonyms:α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester

Chemical Property of α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester

There total 2 articles about α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

α-(1-hydroxycyclohexyl)-2-(benzyloxy)benzeneacetic acid methyl ester (89908-39-4) → α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester (89908-40-7)

Guidance literature:

With Celite; phosphorus pentoxide; In diethyl ether; for 2h;

DOI:10.1021/ja00324a030

Reference yield:

α-(1-hydroxycyclohexyl)-2-(benzyloxy)benzeneacetic acid (89908-38-3) → α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester (89908-40-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / diethyl ether / 0.25 h

2: 75 percent / Celite, P₂O₅ / diethyl ether / 2 h

With Celite; phosphorus pentoxide; In diethyl ether;

DOI:10.1021/ja00324a030

Reference yield: 91.0%

α-(1-cyclohexenyl)-2-(benzyloxy)benzeneacetic acid methyl ester (89908-40-7) → α-(1-cyclohexenyl)-2-hydroxybenzeneacetic acid methyl ester (69515-19-1,86728-22-5,69515-18-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 45h; under 760 Torr;

DOI:10.1021/ja00324a030

upstream raw materials:

α-(1-hydroxycyclohexyl)-2-(benzyloxy)benzeneacetic acid methyl ester

α-(1-hydroxycyclohexyl)-2-(benzyloxy)benzeneacetic acid

Downstream raw materials:

α-(1-cyclohexenyl)-2-hydroxybenzeneacetic acid methyl ester

3-(1-cyclohexenyl)-2-oxo-3H-benzofuran

spiro-3-carboxylic acid methyl ester