N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

Base Information

Chemical Name:N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt
CAS No.:1192312-84-7
Molecular Formula:C₂₇H₃₇N₅O₃*ClH
Molecular Weight:516.083
Hs Code.:

Synonyms:N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

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Chemical Property of N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

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Technology Process of N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

There total 6 articles about N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1192312-83-6
N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide

: 1192312-84-7
N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

Guidance literature:: With hydrogenchloride; In methanol; dichloromethane;

Reference yield:

: 1192313-30-6
ethyl 1-(2-oxo-2-m-tolylethyl)-3-(3-(piperidin-1-yl)propoxy)-1H-pyrazole-5-carboxylate

: 1192312-84-7
N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

Guidance literature:: Multi-step reaction with 5 steps

1: ammonium acetate; acetic acid / 110 °C

2: acetic acid / 110 °C

3: acetic acid / 110 °C

4: tetrabutylammomium bromide; sodium iodide; potassium hydroxide / tetrahydrofuran / 0 - 20 °C / Inert atmosphere of nitrogen

5: hydrogenchloride / methanol; dichloromethane

With hydrogenchloride; ammonium acetate; tetrabutylammomium bromide; acetic acid; sodium iodide; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: C₂₁H₂₈N₄O₃

: 1192312-84-7
N-(1,1-dimethylethyl)-2-[6-(3-methylphenyl)-4-oxo-2-{[3-(1-piperidinyl)propyl]oxy}pyrazolo[1,5-a]pyrazin-5(4H)-yl]acetamide hydrochloride salt

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / 110 °C

2: tetrabutylammomium bromide; sodium iodide; potassium hydroxide / tetrahydrofuran / 0 - 20 °C / Inert atmosphere of nitrogen

3: hydrogenchloride / methanol; dichloromethane

With hydrogenchloride; tetrabutylammomium bromide; acetic acid; sodium iodide; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane;