Technology Process of 5-(naphthalen-2-yl)pentanoic acid
There total 12 articles about 5-(naphthalen-2-yl)pentanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C16H18O2;
With
sodium hydroxide;
In
tetrahydrofuran; methanol; water;
for 6h;
In
tetrahydrofuran; methanol; water;
Acidic conditions;
DOI:10.1021/jm900151e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen / palladium on activated charcoal / methanol / 4 h / 760.05 Torr
2: methanol; sodium hydroxide; water / tetrahydrofuran / 6 h
With
methanol; sodium hydroxide; water; hydrogen;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium aluminium tetrahydride / diethyl ether / 12 h
1.2: 2 h
2.1: [bis(acetoxy)iodo]benzene / 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 2 h
3.1: toluene / 2 h / Heating / reflux
4.1: hydrogen / palladium on activated charcoal / methanol / 4 h / 760.05 Torr
5.1: methanol; sodium hydroxide; water / tetrahydrofuran / 6 h
With
methanol; sodium hydroxide; lithium aluminium tetrahydride; [bis(acetoxy)iodo]benzene; water; hydrogen;
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene;