2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid

Base Information

Chemical Name:2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid
CAS No.:77143-69-2
Molecular Formula:C₁₆H₁₁BrO₄
Molecular Weight:347.165
Hs Code.:
DSSTox Substance ID:DTXSID20998399

Synonyms:BRN 4513712;2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid;5-Benzofuranacetic acid, 2,3-dihydro-3-(4-bromophenyl)-2-oxo-;C16H11BrO4;77143-69-2;DTXSID20998399;LS-34860;[3-(4-Bromophenyl)-2-oxo-2,3-dihydro-1-benzofuran-5-yl]acetic acid

Suppliers and Price of 2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid

Chemical Property:

Vapor Pressure:7.77E-10mmHg at 25°C
Boiling Point:475.2°C at 760 mmHg
Flash Point:241.2°C
Density:1.623g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:345.98407
Heavy Atom Count:21
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2C3=C(C=CC(=C3)CC(=O)O)OC2=O)Br

Technology Process of 2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid

There total 3 articles about 2,3-Dihydro-3-(4-bromophenyl)-2-oxo-5-benzofuranacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 77143-63-6
[3-(4-Bromo-phenyl)-2-oxo-2,3-dihydro-benzofuran-5-yl]-acetic acid methyl ester

: 77143-69-2
[3-(4-Bromo-phenyl)-2-oxo-2,3-dihydro-benzofuran-5-yl]-acetic acid

Guidance literature:: With sulfuric acid; Heating;

Reference yield:

: 14199-15-6
Methyl 4-hydroxyphenylacetate

: 77143-69-2
[3-(4-Bromo-phenyl)-2-oxo-2,3-dihydro-benzofuran-5-yl]-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Na / 1) toluene, reflux, 8 h, 2) reflux, 8 h

2: 52 percent / conc. H₂SO₄ / 24 h / Ambient temperature

3: 62 percent / 50percent aq. H₂SO₄ / Heating

With sulfuric acid; sodium;

Reference yield:

: 77143-79-4
(4-Bromo-phenyl)-(4-methoxycarbonylmethyl-phenoxy)-acetic acid ethyl ester

: 77143-69-2
[3-(4-Bromo-phenyl)-2-oxo-2,3-dihydro-benzofuran-5-yl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / conc. H₂SO₄ / 24 h / Ambient temperature

2: 62 percent / 50percent aq. H₂SO₄ / Heating

With sulfuric acid;