methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

Base Information

Chemical Name:methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate
CAS No.:1012330-65-2
Molecular Formula:C₂₆H₂₄N₂O₅
Molecular Weight:444.487
Hs Code.:

Synonyms:methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

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Chemical Property of methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

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Technology Process of methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

There total 1 articles about methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1012330-64-1
methyl 6-(2-(1-(tert-butyldimethylsilyloxy)-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

: 1012330-65-2
methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.75h;
DOI:10.1021/jm701210y

Reference yield: 91.0%

: 1012330-65-2
methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

: 1012329-58-6
6-{2-[3-(4-phenoxymethyl-phenyl)-propionyl]-oxazol-5-yl}-pyridine-2-carboxylic acid methyl ester

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2.5h;
DOI:10.1021/jm701210y

Reference yield:

: 1012330-65-2
methyl 6-(2-(1-hydroxy-3-(4-(phenoxymethyl)phenyl)propyl)oxazol-5-yl)pyridine-2-carboxylate

: 1012329-59-7
6-{2-[3-(4-phenoxymethyl-phenyl)-propionyl]-oxazol-5-yl}-pyridine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Dess-Martin periodane / dichloromethane / 2.5 h / 20 °C

2: lithium hydroxide; water / tetrahydrofuran / 0.25 h / 20 °C

With lithium hydroxide; water; Dess-Martin periodane; In tetrahydrofuran; dichloromethane;