methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate

Base Information

Chemical Name:methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate
CAS No.:1215021-44-5
Molecular Formula:C₁₈H₃₀O₄Si
Molecular Weight:338.519
Hs Code.:

Synonyms:methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate

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Technology Process of methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate

There total 2 articles about methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1215021-41-2
methyl (S)-(-)-4-(tert-butyldimethylsilyloxy)-2-oxo-3-methylene-4-phenylbutanoate

: 1215021-44-5
methyl (2R,3S,4S)-4-(tert-butyldimethylsilyloxy)-2-hydroxy-3-methyl-4-phenylbutanoate

Guidance literature:: With 5% Pd(II)/C(eggshell); hydrogen; In methanol; at 20 ℃; for 32h; under 760.051 Torr; optical yield given as %ee; diastereoselective reaction;
DOI:10.1021/jo902227f