prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside

Base Information

• Chemical Name: prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside
• CAS No.: 549505-93-3
• Molecular Formula: C₁₈H₂₀O₇S
• Molecular Weight: 380.419
• Mol file: 549505-93-3.mol

Synonyms:prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside

Chemical Property of prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside

There total 3 articles about prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

acetic anhydride (108-24-7) + prop-2-ynyl 2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-2-enopyranoside (389620-75-1) → prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside (549505-93-3)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/S0008-6215(01)00211-7

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside (549505-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / pyridine; DMAP / 6 h

2: 86 percent / pyridine / 20 °C

With pyridine; dmap;

DOI:10.1016/S0008-6215(01)00211-7

Reference yield:

(1-prop-2-ynyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (188605-67-6) → prop-2-ynyl 4-acetyl-2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-enopyranoside (549505-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / pyridine; DMAP / 6 h

2: 86 percent / pyridine / 20 °C

With pyridine; dmap;

DOI:10.1016/S0008-6215(01)00211-7

upstream raw materials:

acetic anhydride

prop-2-ynyl 2,3-dideoxy-6-O-p-toluenesulfonyl-α-D-erythro-hex-2-enopyranoside

p-toluenesulfonyl chloride

(1-prop-2-ynyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside