(1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Base Information

Chemical Name:(1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine
CAS No.:1408314-34-0
Molecular Formula:C₅₀H₅₁IN₂O₁₆
Molecular Weight:1062.86
Hs Code.:

Synonyms:(1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Suppliers and Price of (1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

There total 3 articles about (1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1408314-33-9
C₅₀H₅₂N₂O₁₆

: 1408314-34-0
(1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Guidance literature:: With iodine; sodium hydrogencarbonate; In acetonitrile; at 20 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1021/jo3017378

Reference yield:

: 41355-50-4,51642-81-0,70128-27-7,70145-20-9,94482-21-0,98300-76-6,58484-22-3
2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine

: 1408314-34-0
(1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethylmorpholine; / tetrahydrofuran / 0.17 h / Inert atmosphere

1.2: 0.5 h / Inert atmosphere

2.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

2.2: 10 h / 60 °C / Inert atmosphere

3.1: sodium hydrogencarbonate; iodine / acetonitrile / 20 °C / Inert atmosphere; Schlenk technique

With N-ethylmorpholine;; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; iodine; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo3017378

Reference yield:

: 860567-09-5
2-iodo-5-nitrobenzoic acid chloride

: 1408314-34-0
(1Z,3E)-3-[iodo(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)methylidene]-N-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-nitro-2-benzofuran-1(3H)-imine

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethylmorpholine; / tetrahydrofuran / 0.17 h / Inert atmosphere

1.2: 0.5 h / Inert atmosphere

2.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

2.2: 10 h / 60 °C / Inert atmosphere

3.1: sodium hydrogencarbonate; iodine / acetonitrile / 20 °C / Inert atmosphere; Schlenk technique

With N-ethylmorpholine;; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; iodine; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo3017378