(R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride

Base Information

• Chemical Name: (R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride
• CAS No.: 124078-78-0
• Molecular Formula: C₁₄H₁₄ClNO₅
• Molecular Weight: 311.722

Synonyms:(R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride

Chemical Property of (R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride

Chemical Property:

Purity/Quality:

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Technology Process of (R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride

There total 2 articles about (R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4R)-4-(2-Carboxyethyl)-3-[(phenylmethoxy)carbonyl]oxazolidin-5-one (97975-57-0) → (R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride (124078-78-0)

Guidance literature:

With phosphorus pentachloride; In benzene; at 0 ℃; for 1h;

DOI:10.1021/jo00363a001

Reference yield:

→ (R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride (124078-78-0)

Guidance literature:

Reference yield:

(R)-3-(benzyloxycarbonyl)-5-oxo-4-oxazolidinepropionyl chloride (124078-78-0) → (R)-benzyl 5-oxo-4-(3-oxopropyl)oxazolidine-3-carboxylate

Guidance literature:

With lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; at -78 - 0 ℃;

DOI:10.1021/jm901013a

upstream raw materials:

(4R)-4-(2-Carboxyethyl)-3-[(phenylmethoxy)carbonyl]oxazolidin-5-one

Downstream raw materials:

((R)-1-Carbamoyl-4-oxo-pentyl)-carbamic acid benzyl ester

(R)-5-Oxo-4-(3-oxo-butyl)-oxazolidine-3-carboxylic acid benzyl ester

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