5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Base Information

Chemical Name:5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol
CAS No.:351032-46-7
Molecular Formula:C₄₁H₄₄O₅Si
Molecular Weight:644.883
Hs Code.:

Synonyms:5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Suppliers and Price of 5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

There total 3 articles about 5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 351032-44-5
(3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-2-(4-trimethylsilanyl-buta-1,3-diynyl)-tetrahydro-pyran-2-ol

: 351032-46-7
5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Guidance literature:: With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; acetonitrile; at 0 ℃; for 2.5h;
DOI:10.1002/1522-2675(20010418)84:4<939::AID-HLCA939>3.0.CO;2-A

Reference yield:

: 13096-62-3
(3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one

: 351032-46-7
5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Guidance literature:: Multi-step reaction with 2 steps

1.1: MeLi; LiBr / tetrahydrofuran; hexane / 4.5 h / 20 °C

1.2: 8.55 g / tetrahydrofuran; hexane / 1 h / -78 °C

2.1: BF₃*Et₂O; Et₃SiH / CH₂Cl₂; acetonitrile / 2.5 h / 0 °C

With triethylsilane; boron trifluoride diethyl etherate; methyllithium; lithium bromide; In tetrahydrofuran; hexane; dichloromethane; acetonitrile;
DOI:10.1002/1522-2675(20010418)84:4<939::AID-HLCA939>3.0.CO;2-A

Reference yield:

: 4526-07-2
1,4-bis(trimethylsilyl)-1,3-butadiyne

: 351032-46-7
5,9-anhydro-6,7,8,10-tetra-O-benzyl-1,2,3,4-tetradeoxy-1-(trimethylsilyl)-D-glycero-D-gulo-deca-1,3-diynitol

Guidance literature:: Multi-step reaction with 2 steps

1.1: MeLi; LiBr / tetrahydrofuran; hexane / 4.5 h / 20 °C

1.2: 8.55 g / tetrahydrofuran; hexane / 1 h / -78 °C

2.1: BF₃*Et₂O; Et₃SiH / CH₂Cl₂; acetonitrile / 2.5 h / 0 °C

With triethylsilane; boron trifluoride diethyl etherate; methyllithium; lithium bromide; In tetrahydrofuran; hexane; dichloromethane; acetonitrile;
DOI:10.1002/1522-2675(20010418)84:4<939::AID-HLCA939>3.0.CO;2-A