Technology Process of C29H38O3Si
There total 6 articles about C29H38O3Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; triethylamine; tris-(o-tolyl)phosphine;
In
methanol;
for 1h;
Inert atmosphere;
Reflux;
DOI:10.1021/ol103024z
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 °C
2.1: 1H-imidazole / dichloromethane / 2 h / 0 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C
3.2: 0.5 h / -78 °C
4.1: potassium hexamethylsilazane / 1,2-dimethoxyethane / -78 °C
5.1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / methanol / 1 h / Inert atmosphere; Reflux
With
1H-imidazole; lithium aluminium tetrahydride; oxalyl dichloride; palladium diacetate; potassium hexamethylsilazane; dimethyl sulfoxide; triethylamine; tris-(o-tolyl)phosphine;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane;
3.1: Swern oxidation / 3.2: Swern oxidation / 4.1: Horner-Wadsworth-Emmons olefination / 5.1: Mizoroki-Heck cyclization;
DOI:10.1021/ol103024z
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium hexamethylsilazane / 1,2-dimethoxyethane / -78 °C
2: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / methanol / 1 h / Inert atmosphere; Reflux
With
palladium diacetate; potassium hexamethylsilazane; triethylamine; tris-(o-tolyl)phosphine;
In
methanol; 1,2-dimethoxyethane;
1: Horner-Wadsworth-Emmons olefination / 2: Mizoroki-Heck cyclization;
DOI:10.1021/ol103024z
