C₂₉H₃₀N₄O

Base Information

• Chemical Name: C₂₉H₃₀N₄O
• CAS No.: 1338711-12-8
• Molecular Formula: C₂₉H₃₀N₄O
• Molecular Weight: 450.583
• Mol file: 1338711-12-8.mol

Synonyms:C₂₉H₃₀N₄O

Chemical Property of C₂₉H₃₀N₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₀N₄O

There total 16 articles about C₂₉H₃₀N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C35H32N4O3S (1338711-03-7) → C29H30N4O (1338711-12-8)

Guidance literature:

With ammonia; sodium; In tetrahydrofuran; at -76 ℃; for 0.416667h; Inert atmosphere;

DOI:10.1021/ol202475r

Reference yield:

C26H21BrN2O3 (1338711-08-2) → C29H30N4O (1338711-12-8)

Guidance literature:

Multi-step reaction with 12 steps

1.1: hydrazine hydrate / ethanol / Reflux

2.1: methanol / 24 h / 20 °C

3.1: boron trifluoride diethyl etherate / tetrahydrofuran; dichloromethane / 0.25 h / -40 °C / Inert atmosphere

3.2: 4 h / -40 - 20 °C

4.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

4.2: 0 °C

5.1: tert.-butyl lithium / diethyl ether; pentane / 1.5 h / -40 - 20 °C / Inert atmosphere

6.1: sodium disulfate / tetrahydrofuran / 5 h / 23 °C

6.2: 3 h

7.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 20 °C

7.2: 2 h / 20 °C

8.1: sodium cyanoborohydride / tetrahydrofuran; acetic acid / 1 h / 0 °C

9.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

10.1: sodium azide / N,N-dimethyl-formamide / 95 °C

11.1: triphenylphosphine / toluene / Reflux

12.1: ammonia; sodium / tetrahydrofuran / 0.42 h / -76 °C / Inert atmosphere

With osmium(VIII) oxide; sodium azide; sodium disulfate; boron trifluoride diethyl etherate; ammonia; tert.-butyl lithium; sodium; sodium hydride; sodium cyanoborohydride; hydrazine hydrate; 4-methylmorpholine N-oxide; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; toluene; mineral oil; tert-butyl alcohol; pentane; 11.1: Aza-Wittig reaction;

DOI:10.1021/ol202475r

Reference yield:

tryptamine (61-54-1) → C29H30N4O (1338711-12-8)

Guidance literature:

Multi-step reaction with 15 steps

1.1: toluene / Reflux

2.1: pyridinium perbromide hydrobromide / tetrahydrofuran; chloroform / 2.33 h / -10 °C

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C

3.2: 4 h / 0 - 20 °C

4.1: hydrazine hydrate / ethanol / Reflux

5.1: methanol / 24 h / 20 °C

6.1: boron trifluoride diethyl etherate / tetrahydrofuran; dichloromethane / 0.25 h / -40 °C / Inert atmosphere

6.2: 4 h / -40 - 20 °C

7.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

7.2: 0 °C

8.1: tert.-butyl lithium / diethyl ether; pentane / 1.5 h / -40 - 20 °C / Inert atmosphere

9.1: sodium disulfate / tetrahydrofuran / 5 h / 23 °C

9.2: 3 h

10.1: osmium(VIII) oxide; 4-methylmorpholine N-oxide / tetrahydrofuran; water; tert-butyl alcohol / 20 °C

10.2: 2 h / 20 °C

11.1: sodium cyanoborohydride / tetrahydrofuran; acetic acid / 1 h / 0 °C

12.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

13.1: sodium azide / N,N-dimethyl-formamide / 95 °C

14.1: triphenylphosphine / toluene / Reflux

15.1: ammonia; sodium / tetrahydrofuran / 0.42 h / -76 °C / Inert atmosphere

With osmium(VIII) oxide; sodium azide; sodium disulfate; pyridinium perbromide hydrobromide; boron trifluoride diethyl etherate; ammonia; tert.-butyl lithium; sodium; sodium hydride; sodium cyanoborohydride; hydrazine hydrate; 4-methylmorpholine N-oxide; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; chloroform; water; acetic acid; N,N-dimethyl-formamide; toluene; mineral oil; tert-butyl alcohol; pentane; 14.1: Aza-Wittig reaction;

DOI:10.1021/ol202475r

upstream raw materials:

tryptamine

C₃₅H₃₁N₃O₅S

C₃₅H₃₃N₃O₅S

C₃₅H₃₂N₆O₄S