benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)>

Base Information

• Chemical Name: benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)>
• CAS No.: 131768-77-9
• Molecular Formula: C₄₃H₅₂F₃NO₁₁
• Molecular Weight: 815.881
• Mol file: 131768-77-9.mol

Synonyms:benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)>

Chemical Property of benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)>

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)>

There total 4 articles about benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-O-acetyl-1,5-anhydro-3-O-benzyl-2,6-dideoxy-L-lyxo-hex-1-enitol (106988-71-0,131896-91-8) + benzyl 4-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside (86964-41-2) → benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)> (131768-77-9)

Guidance literature:

With 4 A molecular sieve; trimsyl triflate; triethylamine; In dichloromethane; at -75 ℃;

DOI:10.1016/0008-6215(90)80090-P

Reference yield:

benzyl 2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside (81703-97-1) → benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)> (131768-77-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / trimsyl triflate, powdered molecular sieves (4 Angstroem), triethylamine / CH₂Cl₂ / -60 °C

2: 76 percent / 0.5M aq. NaOH / methanol / 18 h

3: 78 percent / trimsyl triflate, powdered molecular sieves (4 Angstroem), triethylamine / CH₂Cl₂ / -75 °C

With sodium hydroxide; 4 A molecular sieve; trimsyl triflate; triethylamine; In methanol; dichloromethane;

DOI:10.1016/0008-6215(90)80090-P

Reference yield:

4-O-acetyl-1,5-anhydro-3-O-benzyl-2,6-dideoxy-L-lyxo-hex-1-enitol (106988-71-0,131896-91-8) → benzyl 4)-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-(1->4)-(2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside)> (131768-77-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / trimsyl triflate, powdered molecular sieves (4 Angstroem), triethylamine / CH₂Cl₂ / -60 °C

2: 76 percent / 0.5M aq. NaOH / methanol / 18 h

3: 78 percent / trimsyl triflate, powdered molecular sieves (4 Angstroem), triethylamine / CH₂Cl₂ / -75 °C

With sodium hydroxide; 4 A molecular sieve; trimsyl triflate; triethylamine; In methanol; dichloromethane;

DOI:10.1016/0008-6215(90)80090-P

upstream raw materials:

4-O-acetyl-1,5-anhydro-3-O-benzyl-2,6-dideoxy-L-lyxo-hex-1-enitol

benzyl 4-O-(3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside

benzyl 2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside

benzyl 4-O-(4-O-acetyl-3-O-benzyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside