(1R,2R)-(-)-cis-2-Phenylcyclopentanamin

Base Information

• Chemical Name: (1R,2R)-(-)-cis-2-Phenylcyclopentanamin
• CAS No.: 746564-13-6
• Molecular Formula: C₁₁H₁₅N
• Molecular Weight: 161.247
• Mol file: 746564-13-6.mol

Synonyms:(1R,2R)-(-)-cis-2-Phenylcyclopentanamin

Chemical Property of (1R,2R)-(-)-cis-2-Phenylcyclopentanamin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R)-(-)-cis-2-Phenylcyclopentanamin

There total 9 articles about (1R,2R)-(-)-cis-2-Phenylcyclopentanamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

1-phenylethyl 2-methoxyacetate (32786-26-8) + (+/-)-cis-2-phenyl-cyclopentylamine → (R)-1-phenylethanol (1517-69-7) + (1R,2R)-(-)-cis-2-Phenylcyclopentanamin (746564-13-6) + (1S,2S)-(+)-cis-2-Phenylcyclopentanamin + (1R,2R)-N-(2-phenylcyclopentyl)methoxyacetamide

Guidance literature:

With Candida antarctica lipase B; In various solvent(s); at 28 ℃; for 46h; Further byproducts given;

DOI:10.1016/j.tetasy.2003.11.013

Reference yield: 24.0%

1-phenylethyl acetate (93-92-5,50373-55-2) + (+/-)-cis-2-phenyl-cyclopentylamine → (R)-1-phenylethanol (1517-69-7) + (1R,2R)-(-)-cis-2-Phenylcyclopentanamin (746564-13-6) + (1S,2S)-(+)-cis-2-Phenylcyclopentanamin + (1R,2R)-N-(2-phenylcyclopentyl)acetamide

Guidance literature:

With Candida antarctica lipase B; In various solvent(s); at 28 ℃; for 46h; Further byproducts given;

DOI:10.1016/j.tetasy.2003.11.013

Reference yield:

C19H23N → (1R,2R)-(-)-cis-2-Phenylcyclopentanamin (746564-13-6)

Guidance literature:

With hydrogen; acetic acid; In methanol; at 20 ℃; for 18h;

DOI:10.1016/j.bmcl.2014.06.014

upstream raw materials:

methyl methoxyacetate

Benzyl acetate

1-phenylethyl acetate

1-phenylethyl 2-methoxyacetate