1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide

Base Information

• Chemical Name: 1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide
• CAS No.: 15580-20-8
• Molecular Formula: C13H23 N3 O
• Molecular Weight: 237.345
• NSC Number: 163986
• UNII: 9ZEQ3G48DK
• DSSTox Substance ID: DTXSID70165973
• Nikkaji Number: J253.120H
• Wikidata: Q27126418
• Metabolomics Workbench ID: 60375
• ChEMBL ID: CHEMBL1742145
• Mol file: 15580-20-8.mol

Synonyms:1-CMEC;1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide;1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide tosylate;CMCT

Chemical Property of 1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide

Chemical Property:

• Vapor Pressure: 0.000341mmHg at 25°C
• Boiling Point: 319.3°Cat760mmHg
• PKA: 6.90±0.10(Predicted)
• Flash Point: 146.9°C
• PSA: 37.19000
• Density: 1.12g/cm³
• LogP: 1.76310
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 237.184112366
• Heavy Atom Count: 17
• Complexity: 262

Purity/Quality:

98% ^*data from raw suppliers

1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)N=C=NCCN2CCOCC2

Technology Process of 1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide

There total 6 articles about 1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-cyclohexyl-3-(2-morpholin-4-yl-ethyl)-urea (111681-32-4) → 1-cyclohexyl-3-(2-morpholino-ethyl)-carbodiimide (15580-20-8)

Guidance literature:

With potassium carbonate; 4-bromobenzenesulfonyl chloride; N-benzyl-N,N,N-triethylammonium chloride; In benzene; for 3.5h; Heating;

DOI:10.1055/s-1987-27992

Reference yield: 82.0%

(2-morpholin-4-yl-ethyl)-phosphoramidic acid diethyl ester (29326-79-2) + Cyclohexyl isocyanate (3173-53-3) → 1-cyclohexyl-3-(2-morpholino-ethyl)-carbodiimide (15580-20-8)

Guidance literature:

With potassium carbonate; In xylene; for 13h; Heating;

DOI:10.1055/s-1988-27590

Reference yield:

4-(2-AMINOETHYL)MORPHOLINE (2038-03-1) → 1-cyclohexyl-3-(2-morpholino-ethyl)-carbodiimide (15580-20-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 2 h / 20 - 25 °C

2: triphenylphosphine; bromine; triethylamine / dichloromethane / 2 h / 20 °C / Cooling with ice

With bromine; triethylamine; triphenylphosphine; In dichloromethane;

upstream raw materials:

1-Cyclohexyl-3-(2-morpholinoethyl)-2-thiourea

1-cyclohexyl-3-(2-morpholin-4-yl-ethyl)-urea

(2-morpholin-4-yl-ethyl)-phosphoramidic acid diethyl ester

Cyclohexyl isocyanate

Downstream raw materials:

N-cyclohexyl-N'-β-(4-methylmorpholinium)ethylcarbodiimide p-toluenesulfonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 15580-20-8 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide

Send

Send

Metric Ton KG G Pound L ML

Send

Send