<1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid

Base Information

• Chemical Name: <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid
• CAS No.: 138336-36-4
• Molecular Formula: C₁₉H₂₄O₄S
• Molecular Weight: 348.463
• Mol file: 138336-36-4.mol

Synonyms:<1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid

Chemical Property of <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid

There total 3 articles about <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromoacetic acid tert-butyl ester (5292-43-3) → <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid (138336-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / t-BuOK / tetrahydrofuran / Ambient temperature

With potassium tert-butylate; In tetrahydrofuran;

DOI:10.1021/jo00028a034

Reference yield:

thiophenol (108-98-5) → <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid (138336-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / t-BuOK / tetrahydrofuran / Ambient temperature

With potassium tert-butylate; In tetrahydrofuran;

DOI:10.1021/jo00028a034

Reference yield:

tert-butyl (phenylthio)acetate (63006-68-8) + (1R)-cis-hemicaronaldehydic acid (28075-68-5) → <1R,1α,3α(Z)>-2,2-Dimethyl-3-<3-tert-butoxy-3-oxo-2-(phenylsulfenyl)-1-propenyl>cyclopropanecarboxylic Acid (138336-36-4)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo00028a034

upstream raw materials:

tert-butyl (phenylthio)acetate

(1R)-cis-hemicaronaldehydic acid

bromoacetic acid tert-butyl ester

thiophenol

Downstream raw materials:

<1R,1α,3α(Z)>-(3-Phenoxyphenyl)methyl 2,2-Dimethyl-3-<3-tert-butoxy-2-(phenylsulfonyl)-3-oxo-1-propenyl>cyclopropanecarboxylate

<1R,1α,3α(Z)>-(3-Phenoxyphenyl)methyl 2,2-Dimethyl-3-<3-tert-butoxy-2-(phenylsulfenyl)-3-oxo-1-propenyl>cyclopropanecarboxylate