Tecadenoson

Base Information

Chemical Name:Tecadenoson
CAS No.:204512-90-3
Molecular Formula:C₁₄H₁₉N₅O₅
Molecular Weight:337.335
Hs Code.:
UNII:GZ1X96601Z
DSSTox Substance ID:DTXSID80174415
Nikkaji Number:J1.055.589B
Wikidata:Q27088953
NCI Thesaurus Code:C77980
Pharos Ligand ID:XWZBB8BNXVCH
Metabolomics Workbench ID:149353
ChEMBL ID:CHEMBL392149

Synonyms:CVT 510;CVT-510;N-(3-tetrahydrofuranyl)-6-aminopurine riboside;tecadenoson

Suppliers and Price of Tecadenoson

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Tecadenoson

Chemical Property:

Vapor Pressure:7.4E-21mmHg at 25°C
Boiling Point:704.9°C at 760 mmHg
Flash Point:380.1°C
Density:1.89g/cm³
XLogP3:-0.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:337.13861872
Heavy Atom Count:24
Complexity:446

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCC1NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O
Isomeric SMILES:C1COC[C@@H]1NC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O
Recent ClinicalTrials:Safety Study of Tecadenoson to Treat Atrial Fibrillation

Technology Process of Tecadenoson

There total 3 articles about Tecadenoson which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.9%

: 2004-06-0
6-Chloropurine riboside

: 111769-27-8,104530-80-5
(R)-3-aminotetrahydrofuranyl tosylate

: 204512-90-3
Tecadenoson

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tert-butyl alcohol; at 83 ℃; for 27h;
DOI:10.1016/j.bmcl.2007.10.028

Reference yield:

: 309724-86-5
Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-{6-[(R)-(tetrahydro-furan-3-yl)amino]-purin-9-yl}-tetrahydro-furan-3-yl ester

: 204512-90-3
Tecadenoson

Guidance literature:: With ammonia; In methanol;
DOI:10.1016/j.bmcl.2003.09.094

Reference yield:

: 5987-73-5
2',3',5'-O-triacetyl-6-chloroinosine

: 204512-90-3
Tecadenoson

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / ethanol / Heating

2: NH₃ / methanol

With ammonia; triethylamine; In methanol; ethanol;
DOI:10.1016/j.bmcl.2003.09.094