Purine, 2-methyl-

Base Information

• Chemical Name: Purine, 2-methyl-
• CAS No.: 934-23-6
• Molecular Formula: C6H6 N4
• Molecular Weight: 134.13864
• Hs Code.: 2933990090
• NSC Number: 25259
• DSSTox Substance ID: DTXSID30239407
• Nikkaji Number: J101.156A
• Wikidata: Q83121763
• Mol file: 934-23-6.mol

Synonyms:Purine, 2-methyl-;934-23-6;2-Methyl-9H-purine;2-Methylpurine;1H-Purine, 2-methyl-;2-methyl-7h-purine;2-Methyl-1H-purine;methylpurine;2-Methyl-9H-purine #;1H-Purine,2-methyl-(9ci);SCHEMBL375954;DTXSID30239407;NSC25259;NSC 25259;NSC-25259;AKOS006350146

Chemical Property of Purine, 2-methyl-

Chemical Property:

• Vapor Pressure: 0.0803mmHg at 25°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 54.46000
• Density: 1.371g/cm³
• LogP: 0.66130
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 134.059246208
• Heavy Atom Count: 10
• Complexity: 127

Purity/Quality:

≥99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC=C2C(=N1)N=CN2

Technology Process of Purine, 2-methyl-

There total 6 articles about Purine, 2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

6-chloro-2-methyl-9H-purine (100859-35-6) → 2-methyl-9H-purine (934-23-6)

Guidance literature:

With 20% palladium hydroxide-activated charcoal; ammonium formate; In methanol; for 2.5h; Sealed tube; Reflux;

DOI:10.1021/acs.joc.9b01576

Reference yield: 60.0%

1-amino-2-methylpurinium mesitylenesulfonate → 2-methyl-9H-purine (934-23-6)

Guidance literature:

With ammonia; In methanol; at 50 ℃; for 5h; Product distribution; Mechanism; ANRORC mechanism determined by reaction with 15N labelled ammonia; var. temp. and time;

DOI:10.1016/S0040-4020(01)87667-5

Reference yield:

2-methyl-1,7-dihydro-purine-6-thione (38917-31-6) → 2-Methyl-purin (934-23-6)

Guidance literature:

With water; nickel;

DOI:10.1021/ja01510a044

upstream raw materials:

2-methyl-1,7-dihydro-purine-6-thione

6-chloro-2-methyl-7⁽⁹⁾H-purine

5-amino-4,6-dichloro-2-methylpyrimidine

6-chloro-2-methylpyrimidine -4,5-diamine