Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid

Base Information

• Chemical Name: Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid
• CAS No.: 172539-80-9
• Molecular Formula: C₆₀H₇₄O₁₂
• Molecular Weight: 987.24
• Mol file: 172539-80-9.mol

Synonyms:Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid

Chemical Property of Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid

There total 1 articles about Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate (108869-64-3,130177-78-5,129163-12-8) + octyl 3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranoside (163523-05-5) → Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid (172539-80-9)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; In dichloromethane; for 0.5h;

DOI:10.1016/0008-6215(95)00056-Y

Reference yield: 100.0%

Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid (172539-80-9) → Octyl-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid (172539-81-0)

Guidance literature:

With ammonia; In methanol; for 15h;

DOI:10.1016/0008-6215(95)00056-Y

Reference yield:

Octyl-O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid (172539-80-9) → Octyl-O-(3,4,6-tri-O-benzyl-2-O-methyl-α-D-mannopyranosyl)-(1->6)-2,4-di-O-benzyl-β-D-mannopyranosid (172539-83-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / NH₃ / methanol / 15 h

2: 1.) NaH / 1.) DMF, 10 min, 2.) DMF, 30 min

3: 1.) Ir<(COD)(PMePh₂)2>PF₆, 2.) HgO, HgCl₂ / 1.) THF, 5 min, 2.) THF, H₂O, acetone, 30 min

With (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; ammonia; sodium hydride; mercury dichloride; mercury(II) oxide; In methanol;

DOI:10.1016/0008-6215(95)00056-Y

upstream raw materials:

2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate

octyl 3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranoside

Downstream raw materials:

Octyl-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid

Octyl-O-(3,4,6-tri-O-benzyl-2-O-methyl-α-D-mannopyranosyl)-(1->6)-2,4-di-O-benzyl-β-D-mannopyranosid

Octyl-O-(3,4,6-tri-O-benzyl-2-O-methyl-α-D-mannopyranosyl)-(1->6)-3-O-allyl-2,4-di-O-benzyl-β-D-mannopyranosid