6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Base Information

Chemical Name:6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine
CAS No.:188486-38-6
Molecular Formula:C₂₃H₂₃N₅O₇
Molecular Weight:481.465
Hs Code.:

Synonyms:6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Suppliers and Price of 6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

There total 11 articles about 6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 188486-37-5
6-N-benzoyl-9-(2-O-acetyl-3,5-O-isopropylidene-3-C-vinyl-β-D-xylofuranosyl)adenine

: 188486-38-6
6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Guidance literature:: 6-N-benzoyl-9-(2-O-acetyl-3,5-O-isopropylidene-3-C-vinyl-β-D-xylofuranosyl)adenine; With ozone; In dichloromethane; at -78 ℃; for 1h;

With dimethylsulfide; In dichloromethane; at -78 - 20 ℃; for 1h;
DOI:10.1021/ja962974q

Reference yield:

: 9-(3-C-phenylselenocarbonyl-β-D-xylofuranosyl)adenine

: 188486-38-6
6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Guidance literature:: Multi-step reaction with 11 steps

1.1: Bu₃SnH / methanol / 2.5 h / 20 °C / Photolysis

2.1: 50 percent / pyridine / 20 °C

3.1: 100 percent / pyridine / 1 h / 0 - 20 °C

4.1: 100 percent / pyridine / 2 h / 0 - 20 °C

5.1: 100 percent / p-toluenesulfonic acid; EtOH / 1 h / 0 - 20 °C

6.1: 99 percent / Dess-Martin periodinane / CH₂Cl₂ / 72 h / 0 - 20 °C

7.1: CeCl₃ / tetrahydrofuran / 4 h / -78 °C

7.2: 82 percent / tetrahydrofuran / 3 h / -78 °C

8.1: 82 percent / TBAF / tetrahydrofuran / 3 h / 0 °C

9.1: 99 percent / AlCl₃ / diethyl ether / 1 h / 0 - 20 °C

10.1: 97 percent / pyridine / 0 - 20 °C

11.1: ozone / CH₂Cl₂ / 1 h / -78 °C

11.2: 69 percent / Me₂S / CH₂Cl₂ / 1 h / -78 - 20 °C

With pyridine; aluminium trichloride; cerium(III) chloride; ethanol; tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; Dess-Martin periodane; toluene-4-sulfonic acid; ozone; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; 1.1: Reduction / 2.1: silylation / 3.1: silylation / 4.1: benzoylation / 5.1: desilylation / 6.1: Oxidation / 7.1: transmetallation / 7.2: Addition / 8.1: desilylation / 9.1: acetonidation / 10.1: Acetylation / 11.1: ozonolysis / 11.2: Reduction;
DOI:10.1021/ja962974q

Reference yield:

: 65109-11-7
2',5'-bis-O-(tert-butyldimethylsilyl)adenosine

: 188486-38-6
6-N-benzoyl-9-(2-O-acetyl-3-C-formyl-3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

Guidance literature:: Multi-step reaction with 9 steps

1.1: 100 percent / pyridine / 1 h / 0 - 20 °C

2.1: 100 percent / pyridine / 2 h / 0 - 20 °C

3.1: 100 percent / p-toluenesulfonic acid; EtOH / 1 h / 0 - 20 °C

4.1: 99 percent / Dess-Martin periodinane / CH₂Cl₂ / 72 h / 0 - 20 °C

5.1: CeCl₃ / tetrahydrofuran / 4 h / -78 °C

5.2: 82 percent / tetrahydrofuran / 3 h / -78 °C

6.1: 82 percent / TBAF / tetrahydrofuran / 3 h / 0 °C

7.1: 99 percent / AlCl₃ / diethyl ether / 1 h / 0 - 20 °C

8.1: 97 percent / pyridine / 0 - 20 °C

9.1: ozone / CH₂Cl₂ / 1 h / -78 °C

9.2: 69 percent / Me₂S / CH₂Cl₂ / 1 h / -78 - 20 °C

With pyridine; aluminium trichloride; cerium(III) chloride; ethanol; tetrabutyl ammonium fluoride; Dess-Martin periodane; toluene-4-sulfonic acid; ozone; In tetrahydrofuran; diethyl ether; dichloromethane; 1.1: silylation / 2.1: benzoylation / 3.1: desilylation / 4.1: Oxidation / 5.1: transmetallation / 5.2: Addition / 6.1: desilylation / 7.1: acetonidation / 8.1: Acetylation / 9.1: ozonolysis / 9.2: Reduction;
DOI:10.1021/ja962974q