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Tsuduranine

Base Information
  • Chemical Name:Tsuduranine
  • CAS No.:517-97-5
  • Molecular Formula:C18H19NO3
  • Molecular Weight:297.35
  • Hs Code.:
  • Mol file:517-97-5.mol
Tsuduranine

Synonyms:(R)-1,2-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-ol;tuduramine;Tuduranine;Tuduranin;1,2-dimethoxy-6aβ-aporphan-10-ol;4H-Dibenzo[de,g]quinolin-10-ol, 5,6,6a,7-tetrahydro-1,2-dimethoxy-, (R)-;(R)-5,6,6a,7-tetrahydro-1,2-dimethoxy-4H-dibenzo(de,g)quinolin-10-ol;

Suppliers and Price of Tsuduranine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • American Custom Chemicals Corporation
  • TSUDURANINE 95.00%
  • 5MG
  • $ 497.78
Total 5 raw suppliers
Chemical Property of Tsuduranine
Chemical Property:
  • Vapor Pressure:1.67E-10mmHg at 25°C 
  • Melting Point:about 125° (softens at 105°), or 204° 
  • Refractive Index:1.5100 (estimate) 
  • Boiling Point:497.1°C at 760 mmHg 
  • PKA:9.76±0.20(Predicted) 
  • Flash Point:254.4°C 
  • PSA:50.72000 
  • Density:1.237g/cm3 
  • LogP:3.14810 
Purity/Quality:

98%min *data from raw suppliers

TSUDURANINE 95.00% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description This aporphine alkaloid occurs with sinomenine in Sinomenium acutum Rehd. et Wils and was first isolated by Goto from the mother liquors following removal of the former base. The alkaloid is crystalline, softens at 105°C and melts at 125°C. When crystallized from EtOH it has the higher melting point given above. It is laevorotatory with [α]20D - 127.5° (EtOH) and is solu ble in most organic solvents and dilute alkalies. The sparingly soluble hydrochloride has m.p. 286°C (dec.); [α]14.5D - 148° (aqueous MeOH). A phenolic hydroxyl group and an imino group are present and yield a series of derivatives, e.g. the N-methyl methiodide, m.p. 224°C; N-acetyl derivative, m.p. 277°C; [α]18D - 395.24° (MeOH-CHC13); O,N-diacetyl derivative, m.p. 170°C; [α]14D - 321.7° (MeOH); G-methyl ether yielding the N-acetyl compound, m.p. 189°C and the O-ethyl compound which forms a hydrochloride, m.p. 234-6°C; hydrobromide, m.p. 246-8°C and an ethiodide, m.p. l86-7°C. When degraded by the Hofmann process, the alkaloid furnishes a trimethoxyvinylphenanthrene, m.p. 93-5°C.
Technology Process of Tsuduranine

There total 2 articles about Tsuduranine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In acetic acid; for 48h;
DOI:10.1016/S0040-4020(01)81485-X

Reference yield:

Guidance literature:
Stepharine (II)/wss. H2SO4, Δ;
DOI:10.1248/yakushi1947.86.10_871
upstream raw materials:

(R)-(-)-stepharine

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