(2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine

Base Information

• Chemical Name: (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine
• CAS No.: 355381-86-1
• Molecular Formula: C₁₆H₁₈N₂O₄
• Molecular Weight: 302.33
• Mol file: 355381-86-1.mol

Synonyms:(2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine

Chemical Property of (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine

There total 1 articles about (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-dimethoxybenzyl amine (4393-09-3) + 2-nitro-benzaldehyde (552-89-6) → (2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine (355381-86-1)

Guidance literature:

2,3-dimethoxybenzyl amine; 2-nitro-benzaldehyde; In methanol; at 20 ℃; for 1h;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 1h;

DOI:10.1080/00397910500191169

Reference yield:

(2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine (355381-86-1) → 2-nitrobenzaldehyde oxime (3717-25-7,4836-00-4,6635-41-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂O₂; Na₂WO₄ / methanol / 1 h / 20 °C

2: hydroxylamine hydrochloride / methanol; diethyl ether / 4 h / 20 °C

With sodium tungstate; hydroxylamine hydrochloride; dihydrogen peroxide; In methanol; diethyl ether;

DOI:10.1080/00397910500191169

Reference yield:

(2,3-dimethoxy-benzyl)-(2-nitro-benzyl)-amine (355381-86-1) → C-(2-nitrophenyl)-N-(2,3-dimethoxybenzyl)-nitrone (868775-48-8,919112-41-7) + C16H16N2O5

Guidance literature:

With sodium tungstate; dihydrogen peroxide; In methanol; at 20 ℃; for 1h;

DOI:10.1080/00397910500191169

upstream raw materials:

2,3-dimethoxybenzyl amine

2-nitro-benzaldehyde

Downstream raw materials:

C-(2-nitrophenyl)-N-(2,3-dimethoxybenzyl)-nitrone

2-nitrobenzaldehyde oxime