N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine

Base Information

• Chemical Name: N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine
• CAS No.: 1313759-41-9
• Molecular Formula: C₁₆H₁₆N₄
• Molecular Weight: 264.33
• Mol file: 1313759-41-9.mol

Synonyms:N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine

Chemical Property of N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine

There total 1 articles about N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-pyrrole aldehyde (1003-29-8,254729-95-8) + 2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine (60418-47-5) → N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine (1313759-41-9)

Guidance literature:

With formic acid; In toluene; for 6h; Molecular sieve; Reflux;

DOI:10.1016/j.jorganchem.2011.04.028

Reference yield: 74.0%

N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine (1313759-41-9) + diethylzinc (557-20-0) → Zn(N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzeneamine(-1H)) (1313759-43-1)

Guidance literature:

In hexane; toluene; to stirred soln. of benzenamine deriv. in toluene, hexane soln. of ZnEt2added dropwise at 0°C; mixt. warmed to room temp, stirred overni ght; solvent removed in vacuo; residue dissolved in Et2O, filtered, filtrate concd.; elem. anal.;

DOI:10.1016/j.jorganchem.2011.04.028

Reference yield: 63.0%

N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine (1313759-41-9) + trimethylaluminum (75-24-1) → AlMe(N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzeneamine(-1H))*Et2O

Guidance literature:

In hexane; toluene; to stirred soln. of benzenamine deriv. in toluene, hexane soln. of AlMe3added at room temp.; stirred overnight; solvent removed in vacuo; residue dissolved in Et2O, filtered, filtrate concd.; elem. anal.;

DOI:10.1016/j.jorganchem.2011.04.028

upstream raw materials:

2-pyrrole aldehyde

2-(3,5-dimethyl-1H-pyrazol-1-yl)benzenamine

Downstream raw materials:

Zn(N-((1H-pyrrol-2-yl)methylene)-2-(3,5-dimethyl-1H-pyrazol-1-yl)benzeneamine(-1H))