Atropine oxide hydrochloride

Base Information

Chemical Name:Atropine oxide hydrochloride
CAS No.:4574-60-1
Molecular Formula:C17H24ClNO4
Molecular Weight:341.835
Hs Code.:2933990090
European Community (EC) Number:224-959-1
UNII:BI6GBW93CA
DSSTox Substance ID:DTXSID5045384
Wikidata:Q27274672
NCI Thesaurus Code:C142939
ChEMBL ID:CHEMBL2146144
Mol file:4574-60-1.mol

Synonyms:Atropine N-oxide hydrochloride;ATROPINE OXIDE HYDROCHLORIDE;Atropine-N-oxide hydrochloride;4574-60-1;Atropine Oxide HCl;UNII-BI6GBW93CA;Atropine Oxide Hydrochloride [USAN];BI6GBW93CA;DTXSID5045384;EINECS 224-959-1;4574-60-1 (HCl);AMINOXYTROPINE TROPATE HYDROCHLORIDE;Benzeneacetic acid, alpha-(hydroxymethyl)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, 8-oxide, hydrochloride, endo-(+-)-;Atropine oxide hydrochloride (USAN);1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester) 8-oxide hydrochloride;Prestwick_83;Genatropine hydrochloride;NCGC00016649-01;CAS-4574-60-1;C17H23NO4.ClH;CHEMBL2146144;DTXCID3025384;HMS1568E16;Tox21_110544;MFCD00035160;CCG-208421;ATROPINE N-OXIDE HYDROCHLORIDE [WHO-DD];D03011;Q27274672;1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate(ester) 8-oxide hydrochloride;1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-OL (+/-)-TROPATE(ESTER) 8-OXIDE HYDROCHLORIDE;1.alpha.H,5.alpha.H-Tropan-3.alpha.-ol, (.+.)-tropate (ester), 8-oxide, hydrochloride;(1R,3r,5S)-3-(3-hydroxy-2-phenylpropanoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane 8-oxide hydrochloride;[(1S,5R)-8-methyl-8-oxido-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;hydrochloride;Benzeneacetic acid, .alpha.-(hydroxymethyl)- 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester endo-(.+.)-, N-oxide, hydrochloride;BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, 8-OXIDE, HYDROCHLORIDE, ENDO-(+/-)-;Endo-(+-)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate N-oxide hydrochloride;endo-(1)-8-Methyl-8-azabicyclo(3.2.1)oct-3-yl (hydroxymethyl)phenylacetate N-oxide hydrochloride

Suppliers and Price of Atropine oxide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Atropine-N-oxideHydrochloride
100mg
$ 275.00

American Custom Chemicals Corporation
ATROPINE-N-OXIDE HYDROCHLORIDE 98.00%
5G
$ 2107.88

Total 8 raw suppliers

Chemical Property of Atropine oxide hydrochloride

Chemical Property:

Melting Point:192-193oC
PSA：75.96000
LogP:2.70430
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly), Wat
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:341.1393859
Heavy Atom Count:23
Complexity:394

Purity/Quality:

98%Min ^*data from raw suppliers

Atropine-N-oxideHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[N+]1(C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)[O-].Cl
Isomeric SMILES:C[N+]1([C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)[O-].Cl
Uses Anticholinergic.

Technology Process of Atropine oxide hydrochloride

There total 1 articles about Atropine oxide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 51-55-8
Atropine

: 4574-60-1
atropine-N-oxide hydrochloride

Guidance literature:: Atropine; With m-CPBA; In chloroform; at -30 - -20 ℃;

With hydrogenchloride; In chloroform; water;
DOI:10.1016/j.bmcl.2010.06.031

Reference yield: 85.0%

: 4574-60-1
atropine-N-oxide hydrochloride

: 16839-98-8
Noratropine

Guidance literature:: With nanoscale zero-valent iron; In isopropyl alcohol; at 21 ℃; for 3h; Reagent/catalyst; Solvent; Green chemistry;
DOI:10.1039/c7gc00436b

Reference yield: 59.0%

: 4574-60-1
atropine-N-oxide hydrochloride

: 51-55-8
Atropine

: 16839-98-8
Noratropine

Guidance literature:: atropine-N-oxide hydrochloride; With ferrocene; In isopropyl alcohol; at 80 ℃; for 24h;

With sodium hydroxide; In chloroform; water; isopropyl alcohol;
DOI:10.1016/j.bmcl.2010.06.031