N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine

Base Information

Chemical Name:N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine
CAS No.:141397-59-3
Molecular Formula:C20H27 N7 O4
Molecular Weight:429.47288
Hs Code.:
Mol file:141397-59-3.mol

Synonyms:Pyrido[2,3-d]pyrimidine,L-ornithine deriv.

Suppliers and Price of N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：188.25000
Density:1.56g/cm³
LogP:1.85370

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine

There total 17 articles about N(alpha)-(5-deaza-5,6,7,8-tetrahydropteroyl)ornithine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87373-56-6
2-acetamido-6-formyl-4(3H)-oxopyrido<2,3-d>pyrimidine

: 141397-59-3
N^α-(5,6,7,8-tetrahydro-5-deazapteroyl)-L-ornithine

Guidance literature:: Multi-step reaction with 8 steps

1: acetic acid / 18 h / Ambient temperature

2: BH₃*NEt₃ / acetic acid / 0.5 h / 20 - 60 °C

3: 93 percent / H₂O / 1.5 h / 80 °C

4: 46 percent / H₂ / PtO₂*H₂O / trifluoroacetic acid / 18 h / 2280 Torr

5: Et₃N, i-BuOCOCl / dimethylformamide / 0.08 h / Ambient temperature

6: Et₃N, i-BuOCOCl / dimethylformamide

7: 30percent HBr / acetic acid / 0.75 h / Ambient temperature

8: 2N NaOH / 0.5 h / 80 °C

With sodium hydroxide; triethylamine-borane; hydrogen bromide; hydrogen; triethylamine; isobutyl chloroformate; platinum(IV) oxide; In water; acetic acid; N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1021/jm00087a012

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 141397-59-3
N^α-(5,6,7,8-tetrahydro-5-deazapteroyl)-L-ornithine

Guidance literature:: Multi-step reaction with 8 steps

1: acetic acid / 18 h / Ambient temperature

2: BH₃*NEt₃ / acetic acid / 0.5 h / 20 - 60 °C

3: 93 percent / H₂O / 1.5 h / 80 °C

4: 46 percent / H₂ / PtO₂*H₂O / trifluoroacetic acid / 18 h / 2280 Torr

5: Et₃N, i-BuOCOCl / dimethylformamide / 0.08 h / Ambient temperature

6: Et₃N, i-BuOCOCl / dimethylformamide

7: 30percent HBr / acetic acid / 0.75 h / Ambient temperature

8: 2N NaOH / 0.5 h / 80 °C

With sodium hydroxide; triethylamine-borane; hydrogen bromide; hydrogen; triethylamine; isobutyl chloroformate; platinum(IV) oxide; In water; acetic acid; N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1021/jm00087a012

Reference yield:

: 139347-09-4
N²-acetyl-5-deazapteroic acid

: 141397-59-3
N^α-(5,6,7,8-tetrahydro-5-deazapteroyl)-L-ornithine

Guidance literature:: Multi-step reaction with 6 steps

1: 93 percent / H₂O / 1.5 h / 80 °C

2: 46 percent / H₂ / PtO₂*H₂O / trifluoroacetic acid / 18 h / 2280 Torr

3: Et₃N, i-BuOCOCl / dimethylformamide / 0.08 h / Ambient temperature

4: Et₃N, i-BuOCOCl / dimethylformamide

5: 30percent HBr / acetic acid / 0.75 h / Ambient temperature

6: 2N NaOH / 0.5 h / 80 °C

With sodium hydroxide; hydrogen bromide; hydrogen; triethylamine; isobutyl chloroformate; platinum(IV) oxide; In water; acetic acid; N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1021/jm00087a012