(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Base Information

Chemical Name:(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine
CAS No.:1207754-80-0
Molecular Formula:C₁₄H₂₁NO₂S
Molecular Weight:267.392
Hs Code.:

Synonyms:(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Suppliers and Price of (2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 8 raw suppliers

Chemical Property of (2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

There total 8 articles about (2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1207754-79-7
C₁₄H₂₁NOS

: 1207754-80-0
(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In hexane; ethyl acetate; at 0 ℃; for 0.75h;
DOI:10.1016/j.bmcl.2020.127661

Reference yield: 58.0%

: 1207754-82-2
C₇H₁₇NO

: 98-59-9
p-toluenesulfonyl chloride

: 1207754-80-0
(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Guidance literature:: C₇H₁₇NO; p-toluenesulfonyl chloride; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 96h;

With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 4h;

Reference yield:

: 247089-85-6
(R)-p-toluenesulfinamide

: 1207754-80-0
(2R)-2-(1,1-dimethylethyl)-2-methyl-1-[(4-methylphenyl)sulfonyl]aziridine

Guidance literature:: Multi-step reaction with 3 steps

1: titanium(IV) tetraethanolate / 1,2-dichloro-ethane / 70 °C

2: tetrahydrofuran

3: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / ethyl acetate; hexane

With titanium(IV) tetraethanolate; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; hexane; ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1358/dof.2019.44.4.2962844