1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Base Information

Chemical Name:1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone
CAS No.:491839-65-7
Molecular Formula:C₁₅H₁₀BrN₃O₂S
Molecular Weight:376.233
Hs Code.:

Synonyms:1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Suppliers and Price of 1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

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Technology Process of 1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

There total 4 articles about 1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 99-73-0,132309-76-3
para-bromophenacyl bromide

: 15264-63-8
5-(4-pyridinyl)-1,3,4-oxadiazole-2-thiol

: 491839-65-7
1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Guidance literature:: With sodium hydroxide; In ethanol; water; at 20 ℃;
DOI:10.1016/j.bmc.2012.03.061

Reference yield:

: 2459-09-8
4-pyridinecarboxylic acid, methyl ester

: 491839-65-7
1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrazine hydrate / ethanol / Reflux

2.1: potassium hydroxide / ethanol / 24 h / Reflux

2.2: pH 5 - 6

3.1: sodium hydroxide / ethanol; water / 20 °C

With hydrazine hydrate; potassium hydroxide; sodium hydroxide; In ethanol; water;
DOI:10.1016/j.bmc.2012.03.061

Reference yield:

: 55-22-1
pyridine-4-carboxylic acid

: 491839-65-7
1-(4-bromophenyl)-2-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-ylthio)ethanone

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / Reflux

2.1: hydrazine hydrate / ethanol / Reflux

3.1: potassium hydroxide / ethanol / 24 h / Reflux

3.2: pH 5 - 6

4.1: sodium hydroxide / ethanol; water / 20 °C

With sulfuric acid; hydrazine hydrate; potassium hydroxide; sodium hydroxide; In ethanol; water;
DOI:10.1016/j.bmc.2012.03.061