methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

Base Information

Chemical Name:methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate
CAS No.:111923-94-5
Molecular Formula:C₃₁H₃₁N₃O₈S
Molecular Weight:605.668
Hs Code.:

Synonyms:methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

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Technology Process of methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

There total 3 articles about methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 111923-94-5
methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

Guidance literature:

Reference yield:

: 34097-60-4
methyl benzenesulfonylacetate

: 111924-03-9
[1-(4-Diphenylcarbamoyloxycarbonyl-2-methoxy-benzyl)-1H-indazol-6-yl]-carbamic acid cyclopentyl ester

: 111923-94-5
methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 1 h, 2.) 1 h;
DOI:10.1021/jm00171a018

Reference yield:

: 104437-31-2
4-[6-(2-Cyclopentyl-acetylamino)-indazol-1-ylmethyl]-3-methoxy-benzoic acid

: 111923-94-5
methyl 2-[4-[6-(cyclopentyloxycarbonyl)aminoindazol-1-ylmethyl]-3-methoxybenzoyl]-2-phenylsulphonylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / methanol

2: 1.) NaH / 1.) DMF, 1 h, 2.) 1 h

With sodium hydride; triethylamine; In methanol;
DOI:10.1021/jm00171a018