taxamairin B

Base Information

• Chemical Name: taxamairin B
• CAS No.: 110300-77-1
• Molecular Formula: C₂₂H₂₄O₄
• Molecular Weight: 352.43
• Hs Code.: 2914509090
• Mol file: 110300-77-1.mol

Synonyms:TaxamairinB

Chemical Property of taxamairin B

Chemical Property:

• Vapor Pressure: 2.48E-13mmHg at 25°C
• Boiling Point: 577.4°Cat760mmHg
• Flash Point: 252.7°C
• PSA: 52.60000
• Density: 1.17g/cm³
• LogP: 4.21410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of taxamairin B

There total 17 articles about taxamairin B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

8-isopropyl-6,7-dimethoxy-1,1-dimethyl-11,11a-dihydro-1Hdibenzo[a,d][7]annulene-2,10-dione → taxamairin B (110300-77-1)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In toluene; at 80 ℃; for 15h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c03415

Reference yield: 71.0%

8-isopropenyl-6,7-dimethoxy-1,1-dimethyl-1H-dibenzo[a,d]cycloheptene-2,10-dione (168778-67-4) → taxamairin B (110300-77-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

Reference yield:

1,2,10,20-tetrahydrotaxamairin B (168778-66-3) → taxamairin B (110300-77-1)

Guidance literature:

With hydrogen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; Yield given. Multistep reaction; 1.) benzene, reflux, 24 h, 2.) EtOH;

DOI:10.1080/00397919508013864

upstream raw materials:

taxamairin A

dimethyl sulfate

1,2,10,20-tetrahydrotaxamairin B

8-isopropenyl-6,7-dimethoxy-1,1-dimethyl-1H-dibenzo[a,d]cycloheptene-2,10-dione

Refernces

• 1、 Le, Quynh Thuy,Guo, Lihui,Lee, Seung Lyeol,Lee, Junseong,Oh, Chang Ho. "Gold-Catalyzed Synthesis of Icetexane Cores: Short Synthesis of Taxamairin B and Rosmaridiphenol". . p. 9225 - 9228. Retrieved 2020.
• 2、 Wang,Pan,Zhang,Chen. "The total synthesis of taxamairin B". . p. 3413 - 3419. Retrieved 2007/10/03.