5-methyl-1,3-dimethylindole

Base Information

• Chemical Name: 5-methyl-1,3-dimethylindole
• CAS No.: 81784-51-2
• Molecular Formula: C₁₁H₁₃N
• Molecular Weight: 159.231
• Mol file: 81784-51-2.mol

Synonyms:5-methyl-1,3-dimethylindole

Chemical Property of 5-methyl-1,3-dimethylindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-1,3-dimethylindole

There total 1 articles about 5-methyl-1,3-dimethylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1,5-dimethyl-1H-indole (27816-53-1) + C17H19NO2 → 5-methyl-1,3-dimethylindole (81784-51-2)

Guidance literature:

With tris(pentafluorophenyl)borate; In 1,2-dichloro-ethane; at 95 ℃; for 8h;

DOI:10.1021/acscatal.0c01141

Reference yield: 99.0%

5-methyl-1,3-dimethylindole (81784-51-2) + 2-(4-methoxyphenyl)-1-tosylaziridine (155721-36-1) → C27H30N2O3S

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In toluene; at 23 ℃; for 6h; Inert atmosphere;

DOI:10.1021/jacs.8b10217

Reference yield: 97.0%

1-(methylsulfonyl)-4-phenyl-1H-1,2,3-triazole (1135539-10-4) + 5-methyl-1,3-dimethylindole (81784-51-2) → C20H22N2O2S (1431726-33-8)

Guidance literature:

With Rh₂(R-PTAD)₄; In cyclohexane; at 65 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ja4025337

upstream raw materials:

1,5-dimethyl-1H-indole

Downstream raw materials:

C₁₉H₁₇N

C₂₀H₂₂N₂O₂S

((4aS,9aS)-4a,6,9-trimethyl-3-phenyl-4,4a,9,9a-tetrahydro-1H-pyridazino[3,4-b]indol-1-yl)(phenyl)methanone